Therapeutic Target Database is a database to provide information about the known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. Also included in this database are links to relevant databases containing information about target function, sequence, 3D structure, ligand binding properties, enzyme nomenclature and drug structure, therapeutic class, clinical development status. All information provided are fully referenced.
 |
| Statistics of the database |
Therapeutic Target Database allows us to explore therapeutic target information by using search whole database as shown below:
From the search whole database, I have found some useful information about the drugs used to treat Alzheimer's disease. One of the drugs is Rivastigmine. Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions.
 |
| Structure of drug Rivastigmine (Trade name: Exelon) Indication: Alzheimer's disease Therapeutic class: Parasympathomimetics Target: Acetylcholinesterase |
Here is a video about the information of drug Rivastigmine:
No comments:
Post a Comment